Integration of hyperspectral imaging and transcriptomics from individual cells with HyperSeq

Abstract excerpt

Microscopy and omics are complementary approaches to probe the molecular state of cells in health and disease, combining granularity with scalability. While important advances have been achieved over the last decade in each area, integrating both imaging- and sequencing-based assays on the same cell has proven challenging. In this study, a new approach called HyperSeq that combines hyperspectral autofluorescence i...

Topics

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• Gene Expression Profiling
• High-Throughput Nucleotide Sequencing
• High-Throughput Screening Assays
• Phenotype
• RNA-Seq
• Sequence Analysis, RNA
• Single-Cell Analysis
• Spectrum Analysis, Raman

Identifiers and source

Literature Corpus work

af1aa974-47ea-5d6c-a813-40de12cddfc8

DOI

10.1101/2024.01.27.577536