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UBE2T promotes autophagy via the p53/AMPK/mTOR signaling pathway in lung adenocarcinoma

30 Aug 2021

Abstract excerpt

BACKGROUND: Ubiquitin-conjugating enzyme E2T (UBE2T) acts as an oncogene in various types of cancer. However, the mechanisms behind its oncogenic role remain unclear in lung cancer. This study aims to explore the function and clinical relevance of UBE2T in lung cancer. METHODS: Lentiviral vectors were used to mediate UBE2T depletion or overexpress UBE2T in lung cancer cells. CCK8 analysis and western blotting...

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Share to Autophagy in Disease and Therapy
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34461934
DOI: 10.1186/s12967-021-03056-1

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