Article

PhenoGraph: A Multi-Agent Framework for Phenotype-driven Discovery in Spatial Transcriptomics Data Augmented with Knowledge Graphs

2025-06-10

Abstract excerpt

Spatial transcriptomics (ST) provides powerful insights into gene expression patterns within tissue structures, enabling the discovery of molecular mechanisms in complex tumor microenvironments (TMEs). Phenotype-based discovery in ST data holds transformative potential for linking spatial molecular expression patterns to clinical outcomes; however, appropriate ST data analysis remains fundamentally fragmented and...

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Literature Corpus work: ae0dbbf2-9621-51cc-8d2a-9f273dd646c5
DOI: 10.1101/2025.06.06.658341

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