Article

HEAL-KGGen: A Hierarchical Multi-Agent LLM Framework with Knowledge Graph Enhancement for Genetic Biomarker-Based Medical Diagnosis

2025-06-06

Abstract excerpt

<h4>ABSTRACT</h4> The discovery and validation of genetic biomarkers across diverse diseases demand intelligent systems capable of integrating complex multi-omics data with clinical relevance. We introduce HEAL-KGGen, an end-to-end framework that enhances Large Language Models (LLMs) through a hierarchical multi-agent architecture and an automatically constructed medical knowledge graph. The system includes a Gen...

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Literature Corpus work: a295ba32-6ff1-5f2b-9a8c-44b812d25144
DOI: 10.1101/2025.06.03.657521

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