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Transcriptional heterogeneity in cancer-associated regulatory T cells is predictive of survival

2018-11-26

Abstract excerpt

Regulatory T cells (Tregs) are a population of T cells that exert a suppressive effect on a variety of immune cells and non-immune cells. The suppressive effects of Tregs are detrimental to anti-tumor immunity. Recent investigations into cancer-associated Tregs have identified common expression patterns for tumor-infiltration, however the functional heterogeneity in tumor-infiltrating (TI) Treg is largely unknown....

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Literature Corpus work
adf45578-623d-5ca8-8e48-9323ad07f8c6
DOI
10.1101/478628
Open publication

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