Article

Systematic Identification and Validation of ceRNA-driven Regulatory Mechanisms in Pediatric β-Thalassemia Major

2024-12-17

Abstract excerpt

<title>Abstract</title> <p>The involvement of competing endogenous RNA (ceRNA) in β-thalassemia major (β-TM) and their actions on γ-globin is unclear. Here, three types of RNA sequence information—circularRNA (circRNA), microRNA (miRNA), and mRNA—have been largely collected by transcriptome sequencing in β-TM and compared with those of healthy individuals. As <italic>GATA2</italic> is a key transcription factor i...

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Literature Corpus work: acbb833d-2d59-5c4b-92f0-072146d8bace
DOI: 10.21203/rs.3.rs-5366232/v1

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