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Detect <i>de novo</i> expressed ORFs in transcriptomes with DESwoMAN

2025-06-11

Abstract excerpt

De novo gene emergence refers to the process by which new genes arise from mutations in previously non-coding genomic regions. Prior to becoming fixed in a species, newly expressed open reading frames (neORFs) undergo significant turnover within their species of origin. Investigating these early stages of de novo gene emergence is essential for understanding the mechanisms that enable gene formation from scratch....

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Literature Corpus work
ac861af3-25e6-5614-a6b3-1d2c6639027f
DOI
10.1101/2025.06.10.658796
Open publication

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