Article

Detecting predicted cancer-testis antigens in proteomics datasets of healthy and tumoral samples

2024-06-09

Abstract excerpt

<h4>ABSTRACT</h4> Biomarkers are molecular markers found in clinical samples which may aid disease diagnosis or prognosis. High-throughput techniques allow prospecting for such signature molecules by comparing gene expression between normal and sick cells. Cancer-testis antigens (CTAs) are promising candidates for cancer biomarkers due to their limited expression to the testis in normal conditions versus their ab...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ac68b98e-ce93-5a8f-ac3e-1e10c5874f28
DOI: 10.1101/2024.06.08.597624

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Detecting predicted cancer-testis antigens in proteomics datasets of healthy and tumoral samplesDOI 10.1101/2024.06.08.597624Read

Proteomics for the Identification of Biomarkers in Testicular Cancer–ReviewSemantic proximity Read

Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancersSemantic proximity Read

A deep proteome and transcriptome abundance atlas of 29 healthy human tissuesSemantic proximity Read

Bioinformatic identification of proteins with tissue-specific expression for biomarker discoverySemantic proximity Read

Cell Type-Specific Expression of Testis Elevated Genes Based on Transcriptomics and Antibody-Based ProteomicsSemantic proximity Read

A List of Candidate Cancer Biomarkers for Targeted ProteomicsSemantic proximity Read

TNMplot.com: a web tool for the comparison of gene expression in normal, tumor and metastatic tissuesSemantic proximity Read

Assessing the potential relevance of CEACAM6 as a blood transcriptional biomarkerSemantic proximity Read

Investigating normal human gene expression in tissues with high-throughput transcriptomic and proteomic dataSemantic proximity Read

A novel proteomics-based plasma test for early detection of multiple cancers in the general populationSemantic proximity Read

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma.Semantic proximity Read

Increased expression of peptides from non-coding genes in cancer proteomics datasets suggests potential tumor neoantigensSemantic proximity Read