Bioinformatic identification of proteins with tissue-specific expression for biomarker discovery

Abstract excerpt

BACKGROUND: There is an important need for the identification of novel serological biomarkers for the early detection of cancer. Current biomarkers suffer from a lack of tissue specificity, rendering them vulnerable to non-disease-specific increases. The present study details a strategy to rapidly identify tissue-specific proteins using bioinformatics. METHODS: Previous studies have focused on either gene or...

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