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<i>foxe1</i> mutant zebrafish show indications of a hypothyroid phenotype and increased sensitivity to ethanol for craniofacial malformations

2024-02-01

Abstract excerpt

FOXE1 mutations in humans are associated with Bamforth-Lazarus syndrome, characterized by cleft palate and hypothyroidism. Moreover, polymorphisms of FOXE1 are implicated in non-syndromic cleft palate. Much uncertainty still exists about the function of transcription factor FOXE1 in development. To address this, we have previously developed a foxe1 mutant zebrafish demonstrating mineralization defects in larvae....

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Literature Corpus work
ac503fee-3637-5e35-a864-8bc5f1b21180
DOI
10.1101/2024.01.31.578204
Open publication

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<i>foxe1</i> mutant zebrafish show indications of a hypothyroid phenotype and increased sensitivity to ethanol for craniofacial malformationsDOI 10.1101/2024.01.31.578204
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