Back to search

Article

SpotClean adjusts for spot swapping in spatial transcriptomics data

2021-06-12

Abstract excerpt

<h4>Summary</h4> Spatial transcriptomics (ST) is a powerful and widely-used approach for profiling genome-wide gene expression across a tissue with emerging applications in molecular medicine and tumor diagnostics. Recent spatial transcriptomics experiments utilize slides containing thousands of spots with spot-specific barcodes that bind mRNA. Ideally, unique molecular identifiers at a spot measure spot-specific...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ac4e4cc7-797c-55e2-8f84-0a01a36292e3
DOI
10.1101/2021.06.11.448105
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
SpotClean adjusts for spot swapping in spatial transcriptomics dataDOI 10.1101/2021.06.11.448105
Select a neighboring publication to make it the new centre.