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Gut microbiota-derived 5-hydroxyindoleacetic acid from Pumpkin Polysaccharides supplementation alleviates colitis through Epac/Rap1 signaling activation

2023-07-07

Abstract excerpt

<h4>Aims: </h4> Polysaccharides from Pumpkin ( Cucurbita moschata Duchesne) (PP) have many pharmacological activities, including anti-oxidant, immune, and intestinal microbiota regulation. These activities have provided some reminders of its potential therapeutic effect on ulcerative colitis (UC), but this has not yet been confirmed. This study explores the potential modulatory roles of gut microbial metabolites...

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Literature Corpus work
abfbf724-7767-5375-acef-2abc9281aedc
DOI
10.21203/rs.3.rs-3123790/v1
Open publication

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Gut microbiota-derived 5-hydroxyindoleacetic acid from Pumpkin Polysaccharides supplementation alleviates colitis through Epac/Rap1 signaling activationDOI 10.21203/rs.3.rs-3123790/v1
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