Article

Improving Drug Response Prediction Using Dual Similarity Regularization

2021-06-28

Abstract excerpt

Anti-cancer medicine for a particular patient has been a personal medical goal. Many computational models have been proposed by researchers to predict drug response. But predictive accuracy still remains a challenge. Base on this concept which “Similar cells have similar responses to drugs”, we developed the basic method of matrix factorization method by adding fines to similarity. So that the distance of latent f...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: abf32180-6d5f-58ca-974f-ddfed71e2fbf
DOI: 10.21203/rs.3.rs-50015/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Improving Drug Response Prediction Using Dual Similarity RegularizationDOI 10.21203/rs.3.rs-50015/v2Read

A Personalized Cancer Drug Recommendation System with Machine LearningSemantic proximity Read

lncRNA-disease association prediction based on optimizing measures of multi-graph regularized matrix factorization.Semantic proximity Read

Large-Scale Elucidation of Drug Response Pathways in HumansSemantic proximity Read

A Machine Learning Framework for Predicting Drug-drug InteractionsSemantic proximity Read

Computational drug repositioning using similarity constrained weight regularization matrix factorization: A case of COVID ‐19Semantic proximity Read

Drug Response Prediction by Globally Capturing Drug and Cell Line Information in a Heterogeneous Network.Semantic proximity Read

<i>De novo</i> Prediction of Cell-Drug Sensitivities Using Deep Learning-based Graph Regularized Matrix FactorizationSemantic proximity Read

Drug Repurposing through Meta-path Reconstruction using Relationship EmbeddingSemantic proximity Read

Pisces: A multi-modal data augmentation approach for drug combination synergy predictionSemantic proximity Read

Predicting Cancer Drug Response Using a Recommender SystemSemantic proximity Read

Prediction and principle discovery of drug combination based on multimodal friendship featuresSemantic proximity Read

SNF-NN: Computational Method To Predict Drug-Disease Interactions Using Similarity Network Fusion and Neural NetworksSemantic proximity Read