Article

Mutation, selection, and the prevalence of the <i>C. elegans</i> heat-sensitive mortal germline phenotype

2021-12-01

Abstract excerpt

C. elegans strains with the heat-sensitive mortal germline (Mrt) phenotype become progressively sterile over the course of a few tens of generations when maintained at temperatures near the upper range of C. elegans ’ tolerance. Mrt is transgenerationally-heritable, and proximately under epigenetic control. Previous studies have suggested that Mrt presents a relatively large mutational target, and that Mrt is not...

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Literature Corpus work: ab9fc28a-d08c-5cbd-8d3b-2eafbce163ac
DOI: 10.1101/2021.11.29.470498

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