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Protein structures as shapes: Analysing protein structure variation using geometric morphometrics

2017-11-13

Abstract excerpt

A phenotype is defined as an organism’s physical traits. In the macroscopic world, an animal’s shape is a phenotype. Geometric morphometrics (GM) can be used to analyze its shape. Let’s pose protein structures as microscopic three dimensional shapes, and apply principles of GM to the analysis of macromolecules. In this paper we introduce a way to 1) abstract a structure as a shape; 2) align the shapes; and 3) perf...

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Literature Corpus work
aaf00b2c-d03f-5c24-89b8-b5d72d3eca12
DOI
10.1101/219030
Open publication

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Protein structures as shapes: Analysing protein structure variation using geometric morphometricsDOI 10.1101/219030
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