Article

Environmental modifiers of developmental outcomes in genetic epilepsy

2025-12-04

Abstract excerpt

Genetic neurodevelopmental disorders (NDDs) with epilepsy are genome-defined yet exposure-sensitive. While the mechanistic effects of genetic variants underlying these disorders are widely studied to understand clinical heterogeneity among patients, the contribution of external environmental factors remains largely unexplored. Using the Simons Searchlight population dataset, we examined caregiver-reported environm...

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Literature Corpus work: aac16d3b-1529-538e-a179-a25109efddc9
DOI: 10.64898/2025.12.03.25341548

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