Article

Contextual AI models for single-cell protein biology

2023-07-19

Abstract excerpt

Understanding protein function and developing molecular therapies require deciphering the cell types in which proteins act as well as the interactions between proteins. However, modeling protein interactions across biological contexts remains challenging for existing algorithms. Here, we introduce P innacle , a geometric deep learning approach that generates context-aware protein representations. Leveraging a mul...

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Literature Corpus work: a9be0274-bddf-5050-8280-c195c562ef06
DOI: 10.1101/2023.07.18.549602

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