Article

Characterization of Three Variants of SARS-CoV-2 <i>in vivo</i> Shows Host-Dependent Pathogenicity in Hamsters

2022-10-26

Abstract excerpt

<h4>ABSTRACT</h4> Animal models are used in preclinical trials to test vaccines, antivirals, monoclonal antibodies, and immunomodulatory drug therapies against SARS-CoV-2. However, these drugs often do not produce equivalent results in human clinical trials. Here, we show how different animal models infected with some of the most clinically relevant SARS-CoV-2 variants, WA1/2020, B.1.617.2/Delta, B.1.1.529/Omicro...

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Literature Corpus work: ab3bb5c4-ff88-5dd9-9c05-7b5fbe07a2e8
DOI: 10.1101/2022.10.24.513632

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