Article

Six Latent Variables Underlie MDS-UPDRS Scores and Reveal a Dissociation Between Patient- and Clinician-Assessed Parkinson's Disease Symptoms

2026-08-11

Abstract excerpt

The Movement Disorder Society's Unified Parkinson's Disease Rating Scale (MDS-UPDRS) is the global standard for characterising Parkinson's Disease (PD) in clinical contexts. However, the specific symptom phenotypes it captures remain poorly understood, potentially limiting its value for diagnosis, prognosis, and stratifying patients. To address this, we developed a spectral estimation approach to find the unique l...

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Literature Corpus work: a91f2d6d-1b73-5043-aeef-3785cd07a647
DOI: 10.64898/2026.08.10.26360084

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Six Latent Variables Underlie MDS-UPDRS Scores and Reveal a Dissociation Between Patient- and Clinician-Assessed Parkinson's Disease SymptomsDOI 10.64898/2026.08.10.26360084Read

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