Back to search

Article

A Randomized Double-Blind Placebo-Controlled Phase I/II Clinical Trial of a Human Papillomavirus Therapeutic Vaccine, PepCan, for Reducing Head and Neck Cancer Recurrence

2026-01-12

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> Head and neck cancer (HNC) has a high recurrence rate. Safety and effectiveness of PepCan in reducing recurrence for HNC patients were assessed. <h4>Methods and analysis</h4> PepCan consists of four human papillomavirus 16 (HPV 16) E6 peptides and a Candida skin testing reagent (Candin®, Nielsen Biosciences) as a vaccine adjuvant. Since Candida was known to have a general...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a8aab54c-89b1-5908-9d49-da90538731ec
DOI
10.64898/2026.01.09.26343801
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A Randomized Double-Blind Placebo-Controlled Phase I/II Clinical Trial of a Human Papillomavirus Therapeutic Vaccine, PepCan, for Reducing Head and Neck Cancer RecurrenceDOI 10.64898/2026.01.09.26343801
DNA Immunotherapy for Recurrent Respiratory Papillomatosis (RRP): Phase 1/2 study assessing efficacy, safety, and immunogenicity of INO-3107Semantic proximity
DNA immunotherapy for recurrent respiratory papillomatosis (RRP): phase 1/2 study assessing efficacy, safety, and immunogenicity of INO-3107Semantic proximity
Benefits of an immunogenic personalized neoantigen nanovaccine in patients with high-risk gastric/gastroesophageal junction cancerSemantic proximity
Combination of immunotherapy and anti-EGFR agents in immunotherapy refractory head neck cancer recurrent and metastatic head neck squamous cell carcinomaSemantic proximity
A PHARMACOLOGICAL REVIEW ON HEAD AND NECK CANCERSemantic proximity
Octreotide may improve pharyngocutaneous fistula healing through downregulation of cystatins: a pilot studySemantic proximity
Associations between skin rash, treatment outcome, and single nucleotide polymorphisms in head and neck cancer patients receiving the EGFR-inhibitor zalutumumab: results from the DAHANCA 19 trial.Semantic proximity
A Web-Based Survey on Factors for Unvaccination and Adverse Reactions of SARS-CoV-2 Vaccines in Chinese Postoperative Patients With Breast CancerSemantic proximity
Oral Immunotherapy for cashew nut and peanut allergy in children -- a retrospective single-center studySemantic proximity
Safety and Efficacy of the New CryoPop® Cryotherapy Device for Cervical Dysplasia in Low- and Middle-income Countries: Study Protocol for a Multicentre Open-label Non-inferiority Clinical Trial With Historical ControlsSemantic proximity
High-Risk Human Papillomavirus Clearance with a Coriolus Versicolor–Based Vaginal GelSemantic proximity
The SINS trial: a randomised controlled trial of excisional surgery versus imiquimod 5% cream for nodular and superficial basal cell carcinoma.Semantic proximity
Select a neighboring publication to make it the new centre.