Article

CircRNA-mTOR Promotes Hepatocellular Carcinoma Progression and Lenvatinib Resistance via PSIP1/c-Myc Axis Nuclear Translocation and Partially through Increasing EGFR Expression

2023-01-09

Abstract excerpt

<h4>Background: </h4> Hepatocellular Carcinoma (HCC) is one of the major malignant tumors threatening human health. Lenvatinib resistance seriously restricts the efficacy of HCC, but the specific mechanism is not clear. Circular RNA (circRNA) plays an important role in the regulation of tumor drug resistance. Methods Key circRNA was screened by bioinformatics methods, and further identified by relevant validation...

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Literature Corpus work: a85a7a86-549a-54c3-a632-ede23d9c2981
DOI: 10.21203/rs.3.rs-2437109/v1

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