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Crosstalk between circRNAs and the PI3K/AKT signaling pathway in cancer progression

24 Nov 2021

Abstract excerpt

Circular RNAs (circRNAs), covalently closed noncoding RNAs, are widely expressed in eukaryotes and viruses. They can function by regulating target gene expression, linear RNA transcription and protein generation. The phosphoinositide 3-kinase (PI3K)/AKT signaling pathway plays key roles in many biological and cellular processes, such as cell proliferation, growth, invasion, migration, and angiogenesis. It also...

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PMID: 34815385
DOI: 10.1038/s41392-021-00788-w

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