Article
The pathogenic role of the EGFR/STAT5 signaling pathway in synovial fibroblasts of patients with rheumatoid arthritis
2023-03-06
Abstract excerpt
<h4>Objective: </h4> To investigate the role of EGFR/STAT5 signaling pathway in the pathogenesis of rheumatoid arthritis (RA). Method Identifying the differentially expressed genes (DEGs) with bioinformatics analysis. Rheumatoid arthritis fibroblast-like synovial cells (RA-FLS) were collected from patients clinically and cultured in vitro. EGFR and STAT expression levels were detected in tissues using immunohist...
Topics
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- Cancer-related molecular mechanisms research
- Cytokine Signaling Pathways and Interactions
- Ocular Diseases and Behçet’s Syndrome
- Peptidase Inhibition and Analysis
- Research on Leishmaniasis Studies
- Rheumatoid Arthritis Research and Therapies
- Toxin Mechanisms and Immunotoxins
- Ubiquitin and proteasome pathways
Identifiers and source
- Literature Corpus work
- a8126258-12f1-550f-be99-859b839db6c2
- DOI
- 10.21203/rs.3.rs-2627781/v1
