Article

Machine Learning-Enhanced Drug Discovery for BACE1: A Novel Approach to Alzheimer's Therapeutics

2024-09-26

Abstract excerpt

Alzheimer's disease (AD) remains a significant global health challenge, with BACE1, a critical therapeutic target due to its role in the amyloidogenic pathway. This study presents an innovative approach to drug development by integrating machine learning (ML) techniques to identify the potential BACE1 inhibitors. Utilizing a comprehensive dataset of protein-ligand interactions, the current study employed a machine...

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Literature Corpus work: a7f35678-cf9e-575e-a586-74ecef843ab6
DOI: 10.1101/2024.09.24.614844

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