Article

Identification and characterization of an HtrA sheddase produced by <i>Coxiella burnetii</i>

2023-01-26

Abstract excerpt

Having previously shown that soluble E-cadherin (sE-cad) is found in sera of Q fever patients, and that infection of BeWo cells by C. burnetii leads to modulation of the E-cad/β-cat pathway, our purpose was to identify which sheddase(s) might catalyze the cleavage of E-cad. Here, we searched for a direct mechanism of cleavage initiated by the bacterium itself, assuming the possible synthesis of a sheddase encoded...

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Literature Corpus work: a7d9a174-5c7d-55fc-908e-b712a4621e56
DOI: 10.1101/2023.01.26.525556

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