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Transthyretin Amyloid Cardiomyopathy–2025 Update: Current Diagnostic Approaches and Emerging Therapeutic Options

2025-05-26

Abstract excerpt

Transthyretin‐related (ATTR) amyloidosis is a progressive and life‐threatening disease caused by the systemic accumulation of amyloid fibril deposits composed of misfolded transthyretin (TTR) monomers. Clinical manifestations are highly heterogeneous, including symptoms of cardiomyopathy and/or polyneuropathy, depending on the composition and location of fibril deposits. Although ATTR amyloidosis is considered a r...

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Literature Corpus work
a7987491-8222-5586-8b60-2f1d5994da70
DOI
10.20944/preprints202505.2056.v1
Open publication

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