Article
Amyloid Cardiomyopathy.
Heart, lung & circulation - 1 Apr 2020
Bart Nicole K, Thomas Liza, Korczyk Dariusz, Atherton John J, Stewart Graeme J, Fatkin Diane
Abstract excerpt
Amyloid cardiomyopathy is emerging as an important and under-recognised cause of heart failure and cardiac arrhythmias, especially in older adults. This disorder is characterised by extracellular deposition of amyloid fibrils that form due to misfolding of secreted light chains (AL) or transthyretin protein (ATTR). In ATTR, amyloid aggregates typically result from excessive accumulation of wild-type transthyretin...
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