Article

Biomarker discovery study design consistent with the Receiver-Operator Characteristic

2025-04-25

Abstract excerpt

The field of early biomarker discovery is characterized by a lack of consensus on the choice of statistical methodology, which may impede later progress towards clinically useful biomarkers. The Receiver-Operator Characteristic (ROC) is a de facto standard for determining the accuracy of In Vitro Diagnostic (IVD) devices. We demonstrate a biomarker discovery study design that achieves endpoint-consistency through...

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Literature Corpus work: a77a9b9c-3958-5751-b7cd-7df0f5375107
DOI: 10.1101/2025.04.23.25326188

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