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Article

Multiparametric Quantitative Imaging Biomarkers for Phenotype Classification: A Framework for Development and Validation.

Academic radiology - 1 Feb 2023

Delfino Jana G, Pennello Gene A, Barnhart Huiman X, Buckler Andrew J, Wang Xiaofeng, Huang Erich P, Raunig Dave L, Guimaraes Alexander R, Hall Timothy J, deSouza Nandita M, Obuchowski Nancy

Abstract excerpt

This manuscript is the third in a five-part series related to statistical assessment methodology for technical performance of multi-parametric quantitative imaging biomarkers (mp-QIBs). We outline approaches and statistical methodologies for developing and evaluating a phenotype classification model from a set of multiparametric QIBs. We then describe validation studies of the classifier for precision, diagnostic...

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PMID: 36202670
DOI: 10.1016/j.acra.2022.09.004
PMCID: PMC9825632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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