Article

RNA-DNA triplex-forming miRNAs define an evolutionarily recent chromatin regulatory mechanism

2026-02-26

Abstract excerpt

MicroRNAs (miRNAs) are best known for their role in post-transcriptional gene regulation in the cytoplasm. However, a subset of miRNAs has been detected in the nucleus, suggesting additional regulatory functions. Here, we systematically characterize chromatin-associated small non-coding RNAs in the human pancreatic cancer cell line PANC-1. Using chromatin RNA immunoprecipitation coupled with small RNA sequencing,...

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Literature Corpus work: a75cea30-ee97-5570-aba1-d22661b4e13d
DOI: 10.64898/2026.02.25.707792

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