Article

Query Augmented Generation (QAG) from the Genomic Data Commons for Accurate Variant Statistics

2025-09-07

Abstract excerpt

In precision oncology, researchers often use public knowledgebases to check somatic variant frequencies against their cohort data. Large language models (LLMs) can quickly answer questions on somatic variant frequencies, but often hallucinate and give inaccurate results for factual data. Using synthetic queries, we show that somatic variant frequencies in baseline LLM responses are underestimated compared to the G...

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Literature Corpus work: a722c5bd-d01f-5fa5-bedd-4774f3c73449
DOI: 10.1101/2025.09.02.673797

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