Article
Sterculic acid inhibits fenretinide-induced apoptosis in human retinal pigment epithelial cells
2022-08-25
Abstract excerpt
The ratio of saturated to monounsaturated fatty acids, thought to play a critical role in many cellular functions, is regulated by stearoyl-CoA desaturase (SCD), a rate-limiting enzyme in the biosynthesis of monounsaturated fatty acids. Previously, we observed a decrease in both SCD protein and enzymatic activity in apoptosis induced by fenretinide, a synthetic analog of retinoic acid, in the human retinal pigment...
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Identifiers and source
- Literature Corpus work
- a70e9002-4a55-532d-8634-d9c70231b6bd
- DOI
- 10.21203/rs.3.rs-1972330/v1
