Article

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication

2013-09-01

Abstract excerpt

The early steps of HIV-1 replication involve the entry of HIV-1 into the nucleus, which is characterized by viral interactions with nuclear pore components. HIV-1 developed an evolutionary strategy to usurp the nuclear pore machinery and chromatin in order to integrate and efficiently express viral genes. We investigated the role of nucleoporins 153 and 98 (Nup153 and Nup98) in infection of human Jurkat lymphocyte...

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Literature Corpus work: a6570ef6-51f4-534b-a5e9-66a1dc809f25
DOI: 10.1186/1742-4690-10-s1-p111

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