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N6-methyladenosine (m <sup>6</sup> A) RNA modification restrains antifungal immunity and is a therapeutic target in oral candidiasis

2025-09-07

Abstract excerpt

Fungal infections represent a major global threat, yet to date there is a paucity of effective antifungal drugs and no licensed vaccines to any pathogenic fungi. The commensal pathobiont Candida albicans can cause severe oropharyngeal and mucocutaneous infections in immunocompromised individuals. The initial point of interaction of C. albicans in the oral mucosa is with superficial oral epithelial cells (OECs)....

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Literature Corpus work
a62afa42-2168-5cf3-9633-707f2486c862
DOI
10.1101/2025.09.07.674635
Open publication

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N6-methyladenosine (m <sup>6</sup> A) RNA modification restrains antifungal immunity and is a therapeutic target in oral candidiasisDOI 10.1101/2025.09.07.674635
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