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m6A mRNA Methylation Regulates Epithelial Innate Antimicrobial Defense Against Cryptosporidial Infection

6 Jul 2021

Abstract excerpt

Increasing evidence supports that N6-methyladenosine (m 6 A) mRNA modification may play an important role in regulating immune responses. Intestinal epithelial cells orchestrate gastrointestinal mucosal innate defense to microbial infection, but underlying mechanisms are still not fully understood. In this study, we present data demonstrating significant alterations in the topology of host m 6 A mRNA methylome in...

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PMID: 34295340
DOI: 10.3389/fimmu.2021.705232

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