Article

Dihydroartemisinin downregulates the expression of COX-2 in esophageal squamous cell carcinoma through ROS/MAPK/Sp1 axis

2025-11-10

Abstract excerpt

<title>Abstract</title> <p>Background Esophageal squamous cell carcinoma (ESCC) is associated with a poor clinical prognosis due to its highly invasive and metastatic characteristics, as well as chemotherapy resistance, highlighting an urgent need to explore novel therapeutic targets and drugs. Dihydroartemisinin (DHA), a derivative of artemisinin, has been demonstrated to possess broad anti-tumor activity, while...

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Literature Corpus work: a5f7343d-969f-5d32-91f9-4ac48dace85d
DOI: 10.21203/rs.3.rs-7882728/v1

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