Article

Combination of <i>in vivo</i> phage therapy data with <i>in silico</i> model highlights key parameters for treatment efficacy

2021-03-04

Abstract excerpt

<h4>Summary</h4> The clinical (re)development of phage therapy to treat antibiotic resistant infections requires grasping specific biological properties of bacteriophages (phages) as antibacterial. However, identification of optimal dosing regimens is hampered by the poor understanding of phage-bacteria interactions in vivo. Here we developed a general strategy coupling in vitro and in vivo experiments with a...

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Literature Corpus work: a590d100-2460-5051-8647-f2ff512123e1
DOI: 10.1101/2021.03.04.433924

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