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Phage-host-immune system dynamics in bacteriophage therapy: basic principles and mathematical models

1 Jan 2023

Abstract excerpt

Phage therapy is progressively being recognized as a viable alternative to conventional antibiotic treatments, particularly in the context of multi-drug resistant bacterial challenges. However, the intricacies of the pharmacokinetics and pharmacodynamics (PKPD) pertaining to phages remain inadequately elucidated. A salient characteristic of phage PKPD is the inherent ability of phages to undergo replication. In...

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PMID: 38196997
DOI: 10.12793/tcp.2023.31.e17

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