Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An In Vitro Model of Human Red Blood Cell Production From Hematopoietic Progenitor Cells

15 Apr 1998

Abstract excerpt

Hemoglobinopathies, such as beta-thalassemias and sickle cell anemia (SCA), are among the most common inherited gene defects. Novel models of human erythropoiesis that result in terminally differentiated red blood cells (RBCs) would be able to address the pathophysiological abnormalities in erythrocytes in congenital RBC disorders and to test the potential of reversing these problems by gene therapy. We have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Erythrocyte Function and Pathophysiology
Share to Erythropoietin and Anemia Treatment
Share to Hemoglobinopathies and Related Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9531574
DOI: 10.1182/blood.v91.8.2664.2664_2664_2671

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An In Vitro Model of Human Red Blood Cell Production From Hematopoietic Progenitor CellsPMID 9531574Read ↗

Accessory-cell-free differentiation of hematopoietic stem and progenitor cells into mature red blood cellsSemantic proximity Read ↗

Ex-vivo generation of human red cells for transfusionSemantic proximity Read ↗

Erythroid cells in vitro: from developmental biology to blood transfusion productsSemantic proximity Read ↗

Advances in understanding erythropoiesis: evolving perspectivesSemantic proximity Read ↗

Ex vivo generation of fully mature human red blood cells from hematopoietic stem cellsSemantic proximity Read ↗

Human erythroid cells produced ex vivo at large scale differentiate into red blood cells in vivoSemantic proximity Read ↗

Decoding human <i>in vitro</i> terminal erythropoiesis originating from umbilical cord blood mononuclear cells and pluripotent stem cellsSemantic proximity Read ↗

Erythropoiesis: Model systems, molecular regulators, and developmental programsSemantic proximity Read ↗

β-Globin-Expressing Definitive Erythroid Progenitor Cells Generated from Embryonic and Induced Pluripotent Stem Cell-Derived SacsSemantic proximity Read ↗

Ex vivo Production of Human Red Blood Cells From Hematopoietic Stem Cells: What Is the Future in Transfusion?Semantic proximity Read ↗

Primitive and definitive erythropoiesis in mammalsSemantic proximity Read ↗

Concise Review: Stem Cell‐Derived Erythrocytes as Upcoming Players in Blood TransfusionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.