Article

Biochemical characterization of a GDP-mannose transporter from <i>Chaetomium thermophilum</i>

2023-01-13

Abstract excerpt

Nucleotide Sugar Transporters (NSTs) belong to the SLC35 family (human solute carrier) of membrane transport proteins and are crucial components of the glycosylation machinery. NSTs are localized in the ER and Golgi apparatus membranes, where they accumulate nucleotide sugars from the cytosol for subsequent polysaccharide biosynthesis. Loss of NST function impacts the glycosylation of cell surface molecules. Mutat...

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Identifiers and source

Literature Corpus work: a56277ec-9247-5464-a0c4-cf807ef73dca
DOI: 10.1101/2023.01.13.523913

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