Back to search

Article

Genomic investigation of multi-species and multi-variant blaNDM outbreak reveals key role of horizontal IncN and IncX3 plasmid transfer

2023-08-04

Abstract excerpt

<h4>Objectives</h4> New Delhi metallo-beta-lactamases (NDMs) are major contributors to the spread of carbapenem resistance globally. In Australia, NDMs were previously associated with international travel but from 2019 we noted increasing NDM episodes. We conducted an investigation to determine the clinical and genomic epidemiology of NDM-carriage at a tertiary Australian hospital from 2016-2021. <h4>Methods</h4>...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a516ecc4-ce07-5158-80b6-2101b9d6f3a8
DOI
10.1101/2023.08.02.23293478
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genomic investigation of multi-species and multi-variant blaNDM outbreak reveals key role of horizontal IncN and IncX3 plasmid transferDOI 10.1101/2023.08.02.23293478
Genomic epidemiology and transmission dynamics of plasmids carrying New Delhi metallo-β-lactamase ( <i>bla</i> <sub>NDM</sub> ) at a single hospital system over five yearsSemantic proximity
Genomic Epidemiologic Investigation of a Multispecies Hospital Outbreak of NDM-5-Producing Enterobacterales InfectionsSemantic proximity
Multi-species<i>bla</i><sub>NDM</sub>outbreak in multiple tertiary and a primary healthcare facility in Merseyside, UK, driven by a combination of multi-species plasmids and small clonal outbreaksSemantic proximity
The use of whole-genome sequencing for molecular epidemiology and antimicrobial surveillance: identifying the role of IncX3 plasmids and the spread of blaNDM-4-like genes in the Enterobacteriaceae.Semantic proximity
Local transmission and global dissemination of New Delhi Metallo-Beta-Lactamase (NDM): a whole genome analysis.Semantic proximity
Role of the mobilome in the global dissemination of the carbapenem resistance gene blaNDMSemantic proximity
Tracking inter-institutional spread of NDM and identification of a novel NDM-positive plasmid, pSg1-NDM, using next-generation sequencing approachesSemantic proximity
Role of the mobilome in the global dissemination of the carbapenem resistance gene <i>bla</i> <sub>NDM</sub>Semantic proximity
Genomic insights into the tmexCD-toprJ: plasmid-mediated evolution, dissemination and diversity in bacterial populations.Semantic proximity
Real-time genomic epidemiologic investigation of a multispecies plasmid-associated hospital outbreak of NDM-5-producing Enterobacterales infectionsSemantic proximity
Role of mobile genetic elements in the global dissemination of the carbapenem resistance gene blaNDMSemantic proximity
Genomic Epidemiology Insights on NDM-Producing Pathogens Revealed the Pivotal Role of Plasmids on <i>bla</i> <sub>NDM</sub> TransmissionSemantic proximity
Select a neighboring publication to make it the new centre.