Effect of silymarin on lipid and alcohol metabolism in mice following long‐term alcohol consumption

Abstract excerpt

An alcoholic fatty liver disease was induced by feeding an ethanol diet. Eight mice per group were randomly assigned to each following group: (1) control liquid diet + 0.5 mL ddH2O; (2) control liquid diet + 150 mg silymarin/kg body weight (BW) in 0.5 mL ddH2O; (3) ethanol liquid diet + 0.5 mL ddH2O; and (4) ethanol liquid diet + 150 mg silymarin/kg BW in 0.5 mL ddH2O. The ethanol diet...

Topics

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• Disease Models, Animal
• Drug Design
• Liver
• Liver Diseases, Alcoholic
• Molecular Targeted Therapy
• Protective Factors
• Signal Transduction
• Treatment Outcome

Identifiers and source

Literature Corpus work

a4e06432-6b54-5646-a92b-d12f99a45b81

DOI

10.1111/j.1745-4514.2011.00543.x