Article

TurboID proximity interactome mapping reveals NR2E3 association with AP-1 and retinal developmental complexes

2025-09-08

Abstract excerpt

The photoreceptor-specific nuclear receptor NR2E3 is a key transcription factor in the retinal transcriptional network, essential in photoreceptor cell fate and maintenance. Various biallelic loss-of-function variants lead to autosomal recessive inherited retinal disease (IRD), while a single missense variant G56R has been identified to cause autosomal dominant retinitis pigmentosa (adRP). However, a comprehensive...

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Literature Corpus work: a4dd4673-b1da-56fb-8f95-619572647e03
DOI: 10.1101/2025.09.04.674188

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