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Article

Post-transplant inflammatory bowel disease associated with donor-derived TIM-3 deficiency

2023-08-31

Abstract excerpt

<title>Abstract</title> <p>Purpose Inflammatory bowel disease (IBD) occurring following allogenic stem cell transplantation (aSCT) is a very rare condition. The underlying pathogenesis is poorly defined. There is currently no systematic effort to exclude loss- or gain-of-function mutations in immune-related genes in stemcell donors. Methods Whole exome sequencing of hematopoietic cell-intrinsic, donor-derived <...

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Literature Corpus work
a4c92664-8dda-575e-bf20-84db1fe07e04
DOI
10.21203/rs.3.rs-3282819/v1
Open publication

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Post-transplant inflammatory bowel disease associated with donor-derived TIM-3 deficiencyDOI 10.21203/rs.3.rs-3282819/v1
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