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The future of murine sepsis and trauma research models

1 Jun 2015

Abstract excerpt

Recent comparisons of the murine and human transcriptome in health and disease have called into question the appropriateness of the use of murine models for human sepsis and trauma research. More specifically, researchers have debated the suitability of mouse models of severe inflammation that is intended for eventual translation to human patients. This mini-review outlines this recent research, as well as...

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PMID: 26034205
DOI: 10.1189/jlb.5mr0315-127r

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