Article

Synthetic substrates for long-term stem cell culture

2012-04-12

Abstract excerpt

Stem cells have a host of applications in regenerative medicine and basic research. However, clinical translation hinges on the availability of effective stem cell expansion. Stem cell expansion has been limited due to the use of xenogenic factors in the culture system, batch-to-batch variation, and processes that do not readily lend themselves to scale-up. Synthetic substrates represent attractive alternatives to...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a4996409-0217-573b-83be-510490b2f12e
DOI: 10.1016/j.polymer.2012.03.064

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Synthetic substrates for long-term stem cell cultureDOI 10.1016/j.polymer.2012.03.064Read

Biomimetic Culture Strategies for the Clinical Expansion of Mesenchymal Stromal Cells.Semantic proximity Read

Scalable and physiologically relevant microenvironments for human pluripotent stem cell expansion and differentiationSemantic proximity Read

Nanofibrous gelatin substrates for long-term expansion of human pluripotent stem cellsSemantic proximity Read

A thermoresponsive and chemically defined hydrogel for long-term culture of human embryonic stem cellsSemantic proximity Read

Development of substrates for the culture of human pluripotent stem cellsSemantic proximity Read

Biomaterials for the Feeder-Free Culture of Human Embryonic Stem Cells and Induced Pluripotent Stem CellsSemantic proximity Read

Discovery of a Novel Polymer for Xeno-free, Long-term Culture of Human Pluripotent Stem Cell ExpansionSemantic proximity Read

Developing defined substrates for stem cell culture and differentiationSemantic proximity Read

Cell fiber-based three-dimensional culture system for highly efficient expansion of human induced pluripotent stem cellsSemantic proximity Read

Advances in Extracellular Matrix-Mimetic Hydrogels to Guide Stem Cell FateSemantic proximity Read

Tissue engineering and regenerative medicine: a year in review.Semantic proximity Read

Xeno-free culture of human pluripotent stem cells on oligopeptide-grafted hydrogels with various molecular designsSemantic proximity Read