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Secondary structure of pre-mRNA introns for genes in the 15q11-12 locus. Mapping of functionally significant motives for RNA-binding proteins and nucleosome positioning signals

2018-09-05

Abstract excerpt

In this study, we identified reproducible substructures in the folded structures of long intron RNAs for recursive spliced variants and annotated pre-mRNA for GABRB3 and GABRA5 . We mapped the RNA motives recognized by RNA-binding proteins for the specified locus and characterized the area of preferred localization. A comparison of pre-mRNA variants revealed the dominant type of protein potential effects. We dete...

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Literature Corpus work
a44b2dcc-b4b2-5dd9-8b38-660e0d3c6f28
DOI
10.1101/409243
Open publication

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Secondary structure of pre-mRNA introns for genes in the 15q11-12 locus. Mapping of functionally significant motives for RNA-binding proteins and nucleosome positioning signalsDOI 10.1101/409243
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