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Eighteen-year survival after GD2-directed Chimeric Antigen Receptor-Modified Immune Effector Cell Treatment for Neuroblastoma

2024-04-11

Abstract excerpt

<title>Abstract</title> <p>We report long-term outcomes up to 18 years of a clinical trial treating children with neuroblastoma with EBV-specific T lymphocytes and CD3-activated T cells – each expressing a first-generation chimeric antigen receptor targeting GD2 with barcoded transgenes to allow tracking of each population. Of 11 patients with active disease at infusion, three patients achieved a complete respons...

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Literature Corpus work
a4489e1f-7b3b-5d80-bf01-a5b5ba03828d
DOI
10.21203/rs.3.rs-4232549/v1
Open publication

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Eighteen-year survival after GD2-directed Chimeric Antigen Receptor-Modified Immune Effector Cell Treatment for NeuroblastomaDOI 10.21203/rs.3.rs-4232549/v1
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