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Article

GD2 targeting CAR T cells for neuroblastoma

2024-07-11

Abstract excerpt

Treatment of neuroblastoma is a significant clinical unmet need in paediatric oncology epitomised by high-risk disease in which relapse is common and outcomes for children with relapse or primary refractory disease are typically poor, with 4-year progression-free survival for relapse/refractory disease of 6 %. Immunotherapy targeting disialoganglioside GD2 using monoclonal antibodies (mAb) has become a component o...

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Literature Corpus work
473ecc7d-5fb7-559c-882a-62110d55fc09
DOI
10.1016/j.ejcped.2024.100179
Open publication

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GD2 targeting CAR T cells for neuroblastomaDOI 10.1016/j.ejcped.2024.100179
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