Article

Human periventricular nodular heterotopia shows several interictal epileptic patterns, associated with hyperexcitability of neuronal firing

2019-10-24

Abstract excerpt

Periventricular nodular heterotopia (PNH) is a malformation of cortical development that frequently causes drug-resistant epilepsy. The epileptogenicity of ectopic neurons in PNH as well as their role in generating interictal and ictal activity is still a matter of debate. We report the first in vivo microelectrode recording of heterotopic neurons in humans. Highly consistent interictal patterns (IPs) were identi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a43b68eb-080f-57cf-a08c-9a47381be918
DOI: 10.1101/816173

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Human periventricular nodular heterotopia shows several interictal epileptic patterns, associated with hyperexcitability of neuronal firingDOI 10.1101/816173Read

Cerebral Organoids Uncover Mechanisms of Neural Activity Changes in EpileptogenesisSemantic proximity Read

Laser Ablation of Periventricular Nodular Heterotopia for Medically Refractory EpilepsySemantic proximity Read

Modulation of Giant Depolarizing Potentials (GDPs) in Human Large Basket Cells by Norepinephrine and AcetylcholineSemantic proximity Read

Cell-type specific responses to single-pulse electrical stimulation of the human brainSemantic proximity Read

Multi-unit activity and high-gamma patterns dissociate in the seizure onset zone during focal to bilateral tonic-clonic seizuresSemantic proximity Read

Neuronal Hyperactivity in Neurons Derived from Individuals with Grey Matter HeterotopiaSemantic proximity Read

Sporadic periventricular nodular heterotopia: Classification, phenotype and correlation with Filamin A mutations.Semantic proximity Read

Fast oscillations >40Hz localize the epileptogenic zone: an electrical source imaging study using high-density electroencephalographySemantic proximity Read

Harmonic patterns embedded in ictal EEG signals in focal epilepsy: new insight into the epileptogenic zoneSemantic proximity Read

Spontaneous fast-ultradian dynamics of polymorphic interictal events in drug-resistant focal epilepsySemantic proximity Read

Automatic detection of generalized paroxysmal fast activity in Lennox-Gastaut syndrome using a bi-modal EEG time-frequency featureSemantic proximity Read

Human brain organoid networksSemantic proximity Read